| Characteristic | Description |
|---|---|
| Active Ingredients | Tadalafil 20mg, Sildenafil 100mg |
| Mechanism | PDE5 inhibition |
| Formulation | Oral tablet |
| Indication | Erectile dysfunction |
| Onset of Action | 30 to 60 minutes |
| Duration | Up to 36 hours |
| Contraindications | Nitrates, certain medical conditions |
| Common Side Effects | Headache, flushing, dizziness |
| Learn More | |
Chemical Structure
Sildalis is a combination of two active compounds, sildenafil and tadalafil. These compounds belong to the class of phosphodiesterase type 5 (PDE5) inhibitors. The chemical structures of sildenafil and tadalafil allow them to interact with the body’s pathways for nitric oxide, facilitating the flow of blood to the penile region. Sildenafil 100mg and Tadalafil 20mg are combined in one tablet to enhance the therapeutic potential for erectile dysfunction.
Sildenafil features a pyrazolopyrimidinone core while tadalafil is characterized by a benzodioxole moiety. This molecular diversity is key to their synergistic effects. The distinctive structural components enable them to target similar pathways but with varying pharmacokinetics. PubChem provides in-depth data on these molecules.
Mechanism of Action
The dual action of Sildalis stems from its potent inhibition of PDE5. By blocking this enzyme, sildenafil 100mg and tadalafil 20mg increase cyclic guanosine monophosphate (cGMP) levels. Elevated cGMP promotes vasodilation and improved blood flow in the corpus cavernosum. This mechanism results in sustained erections suitable for sexual intercourse.
Sildenafil primarily acts with rapid onset, typically within 30 minutes. Tadalafil provides extended efficacy, lasting up to 36 hours. This combination offers both quick action and prolonged activity, ensuring flexibility in sexual activity timing.
Who Can and Cannot Take Sildalis
Sildalis suits adults with erectile dysfunction. Candidates should have no history of cardiovascular conditions. Those on nitrates or alpha-blockers must avoid it due to potential hypotension risks. Patients with severe renal or hepatic impairment should exercise caution. Consultation with a healthcare professional is advised before initiating treatment.
Individuals with a known allergy to sildenafil or tadalafil should refrain from Sildalis. Its use is contraindicated in cases of recent stroke or myocardial infarction. A thorough medical evaluation will determine its suitability for each patient.
Missed Dose
Sildalis is used as needed, eliminating the concept of a missed dose. If anticipated sexual activity arises without prior administration, the tablet should be taken promptly. It requires adequate time to achieve effectiveness. Spacing doses ensures optimal results and safety.
Avoid doubling doses within a short span. Consistent administration without need could lead to unnecessary adverse effects. Responsible usage adheres to situational requirements rather than a fixed schedule.
How to Cope with Side Effects of Sildalis
Most users experience mild and temporary side effects. These include headache, flushing, and dizziness. Staying hydrated may alleviate discomfort. Remaining seated if dizziness occurs can prevent falls.
Persistent or severe symptoms warrant medical attention. Adjustments in dosage or alternative therapies might be necessary. Monitoring for any visual changes or prolonged erections is crucial. Awareness of potential side effects ensures proactive management.
Purchase Sildalis No Prescription
Sildalis is available online, though it’s advisable to secure it with a prescription. Verification of the product’s legitimacy and ensuring it’s from a reputable source is crucial. Avoid self-prescription to circumvent complications.
- Consultation with a healthcare provider
- Understanding potential interactions
- Assessing individual health conditions
Reliable sources will provide guidance on the appropriate usage of Sildalis. Obtaining it through legitimate means safeguards against counterfeit products. Users should prioritize safety in all healthcare decisions.
Data source:
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- https://www.911mg.org/erectile-dysfunction/tadapox.htm
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